Dipropylene glycol

---

Other names: Dipropylene glycol, oxybispropanol, dihydroxypropyl ether.

Abbreviation: DPG

Molecular formula: C₆H₁₄O₃

Molecular weight: 134.17

Dipropylene glycol has the CAS number 25265-71-8, and is actually a mixture of several isomers: 1,1′-oxobis(2-propanol) (CAS 108-61-2), 2-(2′-hydroxypropoxy)-1-propanol (CAS 106-62-7), and 2,2′-oxobis(1-propanol) (CAS 110-98-5).

Main component structural formula:

Physicochemical properties

Dipropylene glycol is a colorless, transparent, hygroscopic liquid, miscible with water in any proportion, soluble in many organic solvents, miscible with small-molecule aliphatic alcohols and ketones, and slightly soluble or sparingly soluble in hydrocarbon solvents. The n-octanol/water partition coefficient is approximately -1.07 per gram.

Properties and uses

End uses include unsaturated polyester resins, plasticizers, polyols for polyurethanes, alkyd resins, cosmetic ingredients and fragrance extractants, antifreeze, inks and coatings, hydraulic fluids, solvents for ether or ester derivatives, dye intermediates, pesticide intermediates, etc. The main markets are the plasticizer dipropylene glycol dibenzoate and unsaturated polyester resins. In the polyurethane field, it can be used to synthesize polyester polyols, as a chain extender, and as a catalyst for triethylenediamine, etc.

Toxicity

Dipropylene glycol is non-toxic. The acute oral toxicity LD₅₀ in rats is 15 g/kg, and the dermal toxicity LD₅₀ in rabbits is >2 g/kg.